Laboratory of Stem Cell & Regenerative Medicine
Department of Life Science - National Taiwan University
Stem Cells Are Potential.
We Are As Potential As A Stem Cell.
Language
Publication
2022
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Shankar S#, Hsu ZT#, Ezquerra A, Li CC, Huang TL, Coyaud E, Grauffel C, Raught B, Lim C, Lüders J*,Tsai SY*& Hsia KC*. A g-tubulin complex-dependent pathway suppresses unscheduled ciliogenensis by promoting cilia disassembly.Cell Reports. 41 (7):111642 (IF: 10.99; R/C=33/195=16.9%, Cell Biology)
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Lu HA, Lee KZ, Hsu WC, Su LY, Yeh YC, Pan YP, Tsai SY*. 2022 Alternative Splicing Mediated by RNA-binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner. Circulation Research.130(1):112-129. (IF: 25.23; R/C=4/143=2.80%, Cardiac & Cardiovascular).
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Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D; NYSCF Global Stem Cell Array® Team, Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T , Chen S. 2022 A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells. iScience.25(4):104153. (IF: 6.23; R/C=15/74=20.27%, Multidisciplinary)
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Wei YS, Cheng HP, Wu CH, Chang YC, Lin RW, Hsu YT, Chen YT, Lin SL, Tsai SY, Wu SC, Tsai PS. 2022 Oxidative Stress-Induced Alterations of Cellular Localization and Expression of Aquaporin 1 Lead to Defected Water Transport upon Peritoneal Fibrosis.Biomedicines.30;10(4):810. (IF: 5.23, 121/297=40.74%)
2022
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Shankar S#, Hsu ZT#, Ezquerra A, Li CC, Huang TL, Coyaud E, Grauffel C, Raught B, Lim C, Lüders J*,Tsai SY*& Hsia KC*. A g-tubulin complex-dependent pathway suppresses unscheduled ciliogenensis by promoting cilia disassembly.Cell Reports. 41 (7):111642 (IF: 10.99; R/C=33/195=16.9%, Cell Biology)
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Lu HA, Lee KZ, Hsu WC, Su LY, Yeh YC, Pan YP, Tsai SY*. 2022 Alternative Splicing Mediated by RNA-binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner. Circulation Research.130(1):112-129. (IF: 25.23; R/C=4/143=2.80%, Cardiac & Cardiovascular).
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Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D; NYSCF Global Stem Cell Array® Team, Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T , Chen S. 2022 A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells. iScience.25(4):104153. (IF: 6.23; R/C=15/74=20.27%, Multidisciplinary)
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Wei YS, Cheng HP, Wu CH, Chang YC, Lin RW, Hsu YT, Chen YT, Lin SL, Tsai SY, Wu SC, Tsai PS. 2022 Oxidative Stress-Induced Alterations of Cellular Localization and Expression of Aquaporin 1 Lead to Defected Water Transport upon Peritoneal Fibrosis.Biomedicines.30;10(4):810. (IF: 5.23, 121/297=40.74%)
2021
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Hung YC, Huang KL, Chen PL, Li JL, Lu SH, Chang JC, Lin HY, Lo WC, Huang SY, Lee TT, Lin TY, Imai Y, Hattori N, Liu CS,_cc781905-5cde-3194-bb3b- 136bad5cf58d_Tsai SY, Chen CH, Lin CH, Chan CC. 2021 UQCRC1 engages cytochrome c for neuronal apoptotic cell death.Cell Reports.36(12):109729
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Anand A, Tseng HC, Chian HC, Hsu WH, Liao YF, Lu SH,Tsai SY, Pan CY, Chen YT. 2021 Significant Elevation in Potassium Concentration Surrounding Stimulated Excitable Cells Revealed by an Aptamer-Modified Nanowire Transistor.ACS Applied Bio Materials.4(9):6865-6873
2020
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Tsai SY*, Ghazizadeh Z, Wang HJ, Ortega FA, Badieyan ZS, Hsu ZT, Gordillo M, Kumar R, Christini DJ, Evans T* and Chen S*.2020A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity.Cardiovascular Research.116(3):658-670 (Co-first author and Co- Corresponding author). (IF: 6.86; R/C=12/138=8.69%, Cardiac & Cardiovascular).
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Hsu YT, Wu CH, Chao CY, Wei YS, Chang YC, Chen YT, Lin SL, Tsai SY, Lee YJ, Tsai PS.2020Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1β-CX3CL1-TGFβ1 signal axis.Sci Rep.10(1):11496. (IF: 4.576; R/C=17/71=23.94%, Multidisciplinary).
2019
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Chang CC, Chen CJ, Grauffe C, Pien YC, Lim C,Tsai SY. Hsia KC. 2019 Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α. Nature Communications. 10(1):4307 (Co-Corresponding author). (IF: 13.81; R/C=5/69, Multidisciplinary)
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Tsai SY, Ghazizadeh Z, Wang HJ, Ortega FA, Badieyan ZS, Hsu ZT, Gordillo M, Kumar R, Christini DJ, Evans T* and Chen S*. 2019 A Human Embryonic Stem Cell Reporter Line for Monitoring Chemical-induced Cardiotoxicity. Cardiovascular Research . pii: cvz148. (Co-first author and Co-Corresponding author). (IF: 6.23; R/C=12/136, Cardiac & Cardiovascular)
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Yang SC, Liu JJ#, Wang CK#, Lin YT#,Tsai SY, Chen WJ, Huang WK, Tu PA, Lin YC, Chang CF, Cheng CL, Lin H, Lai CY, Lin CY, Lee YH, Chiu YC, Hsu CC, Hsu SC, Hsiao M, Schuyler SC, Lu FL*, Lu J*. 2019 Downregulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. FASEB J. 33(9):10577-10592. (Third author). (IF: 5.42; R/ C=8/87, Biology)
2018
Chang CW, Chang CC, Hsia KC,Tsai SY*. 2018 Generation of FHL2 homozygous knockout lines from human embryonic stem cells by CRISPR/Cas9-mediated ablation. Stem Cell Research 23;27:21-24. (Corresponding auth or). (IF: 4.18; R/C=ank: 34/162, Biotechnology & Applied Microbiology)
2017
Chang, CC, Huang, TL, Shimamoto, Y.,Tsai, SY, and Hsia, KC (2017). Regulation of mitotic spindle assembly factor NuMA by Importin-beta. The Journal of cell biology 216, 3453-3462.
Crespo M, Vilar E,Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S*. (2017) Colonic organisms derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nature Medicine. Jul; 23(7):878-884.
Tsai SY*, Chen S, and Evans T. (2017) Efficient Generation of Cardiac Purkinje-like Cells from
Embryonic Stem Cells by Activating cAMP Signaling. Current Protocols in Stem Cell Biology.
40:1F.16.1-1F.16.13. (Corresponding author).
2016
Feng L#, Cook B#,Tsai SY#, Zhou T#, LaFlamme B, Evans T* and Chen S*. (2016) Discovery of a Small- Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation. Cell Reports 15(9):2063-2075. (Co-first author)
Simsek S, Zhou T, Robinson CL,Tsai SY, Lin X, Hon J, Evans T and Chen S*. (2016) Modeling Cystic Fibrosis using PSC-derived Human Pancreatic Duct Epithelial Cells. Stem Cells Translational Medicine Pii:sctm. 2015-0276.
2015
Tsai SY, Maass K, Lu J, Fishman GI *, Chen S*, and Evans T*. (2015) Efficient generation of cardiac purkinje cells from ESCs by Activating cAMP Signaling. Stem Cell Reports. pii: S2213-6711(15)00127-7.
2014
Casalena G, Krick S, Daehn I, Yu L, Ju W, Shi S,Tsai SY, D'Agati V, Lindenmeyer M, Cohen CD, Schlondorff D, Bottinger EP*. (2014) Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro. American Journal of Physiology- Renal Physiology. 306(11) :F1372-80.
Tsai SY#, Sennett R#, Rezza A, Clavel C, Grisanti L, Zemla R, Najam S, Rendl M*. (2014) Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation. Developmental Biology. 385(2):179-88.
2013
Turbendian HK#, Gordillo M#,Tsai SY, Lu J, Kang G, Liu TC, Tang A , Liu S, Glenn I. Fishman GI, and Evans T*. (2013) GATA factors efficiently direct cardiac fate from ESCs. Development. 140(8):1639-44.
2012
Grisanti L, Clavel C, Cai X, Rezza A,Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M*. (2012) Tbx18 Targets Dermal Condensates for Labeling, Isolation, and Gene Ablation during Embryonic Hair Follicle Formation. Journal of Investigative Dermatology. 133(2):344-53
2011
Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR and Rendl M*. (2011) Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells. 29(6):964-71 .
Ang YS,Tsai SY, Lee DF, Monk J, Su J, Ratnakumar K, Ding J, Ge Y, Darr H, Chang B, Wang J, Rendl M, Bernstein E, Schaniel C, Lemischka IR*. (2011) Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell. 145(2): 183-97.
2010
Tsai SY, Clavel C, Kim S, Ang YS, Grisanti L, Lee DF, Kelley K, Rendl M*. (2010) Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells. Stem Cells. 28(2):221-8 .
2008
Krick S, Shi S, Ju W, Faul C,Tsai SY, Mundel P, Böttinger EP*. (2008) Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease. Proc. Natl. Acad. Sci.105(37):14106-11.
2003
Chen CF*,Tsai SY, Ma MC, Wu MS. (2003) Hypoxic preconditioning enhances renal superoxide dismutase levels in rats. The Journal of Physiology. 552(Pt 2):561-9.